During the COVID-19 pandemic, civil society organizations (CSOs) in Nepal are closely monitoring and responding to the emerging health and socio-economic needs of communities on the ground. This Gender Equality Update focuses on the COVID-19 response of four CSOs and women’s networks that are part of the Gender in Humanitarian Action Task Team (GiHA TT) chaired by UN Women. It highlights their valuable efforts to promote and protect the rights of the most excluded and vulnerable groups in Nepal during these unprecedented times.